The current study examined changes in anxiety sensitivity following cognitive behavior therapy as a pre- dictor of treatment outcome in patients with social anxiety disorder (SAD) and patients with panic disorder (PD). One- hundred ninety-seven patients with a principal diagnosis of SAD ( n = 108) or PD ( n = 89) completed the Anxiety Sensitivity Index (ASI; Reiss et al in Behav Res Ther 24:1–8, 1986 ), Depression Anxiety Stress Scales (DASS- 21; Lovibond and Lovibond in Behav Res Ther 33:335–343, 1995 ), Social Phobia Inventory (SPIN; Con- nor et al in Br J Psychiatry 176:379–386, 2000 ) and Panic Disorder Severity Scale - Self Report (PDSS-SR; Houck et al in Depress Anxiety 15:183–185, 2002 ; Shear et al in Am J Psychiatry 154:1571–1575, 1997 ) pre and post dis- order specific treatment. For the SAD group, changes on ASI Physical and ASI Social subscales made significant contributions to the prediction of posttreatment social anxiety symptoms over and above pretreatment social anxiety symptoms and changes in depression scores. For the PD group, changes on the ASI Physical subscale made a significant contribution to the prediction of posttreatment panic symptoms over and above pretreatment panic symptoms and changes in depression scores. The present study provides further support that, while the global construct of anxiety sensitivity is a transdiagnostic factor across the anxiety disorders, the lower-order dimensions of anxiety sensitivity have specificity for particular anxiety disorders.
