Low fertility and inefficient management of sub-Saharan African soils have been the major challenges facing productivity among smallholder farmers. Unfortunately, inorganic fertiliser used as major soil nutrient management is unsustainable, causing soil degradation and environmental pollution. Therefore, smallholder farmers may only realise their maximum potential if a more sustainable, low-cost and efficient integrated nutrient management system compatible with their socioeconomic status is practised. Currently, the increasing demand for sustainable agriculture is driving the use of biological fertilisers, which are composed of beneficial microorganisms; ranging from bacteria to blue-green algae and fungi. Biofertilisers such as Rhizobium, Azotobacter, Azospirillum, Pseudomonas and Bacillus have invaluable use in sustainable agriculture owing to their environmentally- friendliness, cost-effectiveness and improved productivity benefits. They improve plant nutrition and yield through biological nitrogen fixation, nutrient solubilisation, biocontrol activities and production of plant growth promoting substances.